(54) Methods of Using Bacillus Anthracis Other Publications Protective Antigen Sequences for Vaccination
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W0 WO 01/21656 A2 W0 WO 01/82788 A2 3/2001 11/2001 Puziss et al (Journal of Bacteriology, v01. 85, 1963, p. 230-236).* Ramirez et al (Abstract of SIM Meeting, Nov. 1, 2001).* Skolnick et a1. (Trends in Biotechnology 18: 34-39, 2000).* Boslego et al (Vaccines and lmmunotherapy, 1991, Chapter 17).* Ellis (Vaccines, W.B. Saunders Company, Chapter 29, 1988, pp. 568-574).* Ahuja et al., “Rapid puri?cation of recombinant anthrax-protective antigen under nondenaturing conditions,” Biochem. Biophys. Res. Commun. 286:6-11, 2001. Baillie et al., “The expression of the protective antigen of Bacillus anthracis in Bacillus subtilis, ” J Appl. Microbiol. 84: 74 1 -746, 1998. Bartkus et al., “Transcriptional regulation of the protective antigen gene ofBacillus anthracis,”Infect. Immun. 57:2295-2300, 1989. Boslego et al. Vaccines and lmmunotherapy, 1991, Chapter 17. Bowie et al., “Decipering the Message in Protein Sequences: Toler ance to Amino Acid Substitutions,” Science 247: 1306-13 10, 1990. Chase, H.A., “Puri?cation of proteins by adsorption chromatography in expanded beds,” Trends Bi0techn0l. 12:296-303, 1994. Chauhan et al., “Constitutive expression of protective antigen gene of Bacillus anthracis in Escherichia c0li,” Biochem. Biophys. Res. Commun. 283:308-315, 2001. Chu et al., “Preparation, characterization, and immunogenicity of conjugates composed of the O-speci?c polysaccharide of Shigella dysenteriaetype 1 (Shiga’ s Bacillus) bound to tetanus toxoid,” Infect. Immun. 59:4450-4458, 1991. Coulson et al., “Bacillus anthracis protective antigen, expressed in Salmonella typhimurium SL 3261, affords protection against anthrax spore challenge,” Vaccine 12:1395-1401, 1994. Creighton, Thomas E., in his book, “Proteins: Structures and Molecu lar Properties,” 1984 (pp. 314-315). Creighton, Thomas E., in his book “Protein Structure: A Practical Approach,” 1989, (pp. 184-186). de Veth and Kolver, “Digestion of Ryegrass Pasture in Response to Change in pH in Continuous Culture,” J. Dairy Sci. 84:1449-1457, 2001. Ellis. Vaccines, W.B. Saunders Company, Chapter 29, 1988, pp. 568-574. Ezzell and Welkos, “The capsule of Bacillus anthracis, a review,” J. Appl. Microbiol. 87:250, 1999. Farchaus et al., “Puri?cation and characterization of the major sur face array protein from the avirulentBacillus anthracis Delta Sterne 1,” J. Bacteriol. 177:2481-2489, 1995. Farchaus et al., “Fermentation, puri?cation, and characterization of protective antigen from a recombinant, avirulent strain of Bacillus anthracis,”Appl. Environ. Microbiol. 64:982-991, 1998. Fellows et al., “Ef?cacy of a human anthrax vaccine in guinea pigs, rabbits, and rhesus macaques against challenge byBacillus anthracis isolates of diverse geographical origin,” Vaccine 19:3241-3247, 2001.
منابع مشابه
Construction of a Eukaryotic Plasmid Encoding Bacillus anthracis Protective Antigen, a Candidate for DNA Vaccine
Background: DNA immunization with plasmid DNA encoding bacterial, viral, parasitic and tumor antigens has been reported to trigger protective immunity. Objective: To evaluate the use of a DNA immunization strategy for protection against anthrax, a plasmid was constructed. Methods: The partialsequence of protective antigen of Bacillus anthracis, amino acids 175-764, as a potent immunogenic targe...
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Introduction: Shigella enterotoxin(STxB) is one of the major virulent factors in Shigella dysenteriae type 1 and E. coli O157:H7, which its immunogenicity, adjuvant and delivery characteristic have been proven. Anthrax is a common disease in humans and animals and identifies domain a-1 antibodies of protective antigen(PA) which is 62% of the PA antigens of Bacillus anthracis. Therefore, the pur...
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تاریخ انتشار 2014